Greek track left four set points in a row unused in the tiebreak of the first set. He led 6-2, but lost six consecutive runs. He led 3-1 in the second set.
The 25-year-old Greek track was in the main tournament in Paris for the first time. In the opening round he had caused a surprise by eliminating Spaniard Alejandro Davidovich Fokina, who made the last eight last year.
Nakashima (20), who had never won a match in Paris, will face German Alexander Zverev in the third round. He survived a match point against the Argentinian Sebastián Báez.
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